CH TECHNOLOGIES  |  PUBLICATIONS

2009

           Crystal L. Loving, Taruna Khurana, Manuel Osorio, Gloria M. Lee, Vanessa K. Kelly, Scott Stibitz and Tod J. Merkel. Role of Anthrax Toxins in Dissemination, Disease Progression, and Induction of Protective Adaptive Immunity in the Mouse Aerosol Challenge Model. Infect. Immun. January 2009 vol. 77 no. 1 255-265. (BANG, CH Tech NOIES, Infectious agents)

           Crystal L. Loving, Manuel Osorio, Yun-Gi Kim, Gabriel Nuñez, Molly A. Hughes and Tod J. Merkel. Nod1/Nod2-Mediated Recognition Plays a Critical Role in Induction of Adaptive Immunity to Anthrax after Aerosol Exposure. Infect. Immun., October 2009, vol. 77, no. 10, 4529-457. (BANG, CH Tech NOIES, Infectious agents)

           Dae Jin Song, Myung Goo Min, [...], and David H. Broide. Environmental tobacco smoke exposure does not prevent corticosteroids reducing inflammation, remodeling, and airway hyperreactivity in mice exposed to allergen. American Journal of Physiology - Lung Cellular and Molecular Physiology, Aug 2009; 297(2): L380-L387. (Cigarette smoke, CSM-SSM)

           Se-Ran Yang, Hongwei Yao, Saravanan Rajendrasozhan, Sangwoon Chung, Indika Edirisinghe, Samantha Valvo, George Fromm, Michael J. McCabe, Jr., Patricia J. Sime, Richard P. Phipps, Jian-Dong Li, Michael Bulger and Irfan Rahman. RelB Is Differentially Regulated by IκB Kinase-α in B Cells and Mouse Lung by Cigarette Smoke. Am J Respir Cell Mol Biol, Feb 2009, 40(2):147-158. (Cigarette smoke, 30 Port Automatic Smoking Machine)

           D. Saini, R. M. Buller, A. S. Biris and P. Biswas. Characterization of a Nose-Only Inhalation Exposure System for Ectromelia Virus Infection of Mice. Particulate Science and Technology: An International Journal, Volume 27, Issue 2, 2009, p.152-165. (BANG, CH Tech NOIES)

           Matthew J. Panzner, Khadijah M. Hindi, Brian D. Wright, Jane B. Taylor, Daniel S. Han, Wiley J. Youngs and Carolyn L. Cannon. A theobromine derived silver N-heterocyclic carbene: synthesis, characterization, and antimicrobial efficacy studies on cystic fibrosis relevant pathogens. Dalton Transactions, Issue 35: 7308-7313, 2009. (CH Tech NOIES)

           John T. Bernert, Sydney M. Gordon, Ram B. Jain, Marielle C. Brinkman, Connie S. Sosnoff, Tiffany H. Seyler, Yang Xia, James E. McGuffey, David L. Ashley, James L. Pirkle, Eric J. Sampson. Increases in tobacco exposure biomarkers measured in non-smokers exposed to sidestream cigarette smoke under controlled conditions. Biomarkers, March 2009, Vol. 14, No. 2, Pages 82-93. (Cigarette Smoke, 30 Port Automatic Smoking Machine)

           Shanshan Cai, Rachel L. Zemans, Scott K. Young, G. Scott Worthen, and Samithamby Jeyaseelan. Myeloid Differentiation Protein-2–Dependent and –Independent Neutrophil Accumulation during Escherichia coli Pneumonia. Am J Respir Cell Mol Biol. Jun 2009; 40(6): 701–709. (BANG, CH Tech NOIES)

           Khadijah M. Hindia, Andrew J. Dittob, Matthew J. Panznera, Douglas A. Medvetza, Daniel S. Hanc, Christine E. Hovisc, Julia K. Hilliardc, Jane B. Taylorc, Yang H. Yunb, Carolyn L. Cannonc, Wiley J. Youngsa. The antimicrobial efficacy of sustained release silver–carbene complex-loaded l-tyrosine polyphosphate nanoparticles: Characterization, in vitro and in vivo studies. Biomaterials, Volume 30, Issue 22, August 2009, Pages 3771–3779. (CH Tech NOIES)

           Michelle Natiello, George Kelly, James Lamca, David Zelmanovic, Richard W. Chapman, Jonathan E. Phillips. Manual and automated leukocyte differentiation in bronchoalveolar lavage fluids from rodent models of pulmonary inflammation. Comparative Clinical Pathology, May 2009, Volume 18, Issue 2, pp 101-111. (Cigarette Smoke, 30 Port Automatic Smoking Machine)

           Jorrit J Hofstra, Alexander D Cornet, Bart F de Rooy, Alexander P Vlaar, Tom van der Poll, Marcel Levi, Sebastian AJ Zaat and Marcus J Schultz. Nebulized antithrombin limits bacterial outgrowth and lung injury in Streptococcus pneumonia pneumonia in rats. Critical Care, 2009, 13:R145. (CH Tech NOIES)

           Sheung P. Ng, Daniel J. Conklin, Aruni Bhatnagar, Duane D. Bolanowski, Jessica Lyon, and Judith T. Zelikoff. Prenatal Exposure to Cigarette Smoke Induces Diet- and Sex-Dependent Dyslipidemia and Weight Gain in Adult Murine Offspring. Environ Health Perspect. Jul 2009; 117(7): 1042–1048. (Cigarette Smoke, 30 Port Automatic Smoking Machine)

           Jenny Rissler, Lars Asking, and Jakob Kisbye Dreyer. A Methodology to Study Impactor Particle Reentrainment and a Proposed Stage Coating for the NGI. Journal of Aerosol Medicine and Pulmonary Drug Delivery. December 2009, 22(4): 309-316. (Vilnius Aerosol Generator)

           John Doukas, Lisa Eide, Karin Stebbins, Adrienne Racanelli-Layton, Luis Dellamary, Michael Martin, Elena Dneprovskaia, Glenn Noronha, Richard Soll, Wolfgang Wrasidlo, Lisette M. Acevedo and David A. Cheresh. Aerosolized Phosphoinositide 3-Kinase γ/δ Inhibitor TG100-115 [3-[2,4-Diamino-6-(3-hydroxyphenyl)pteridin-7-yl]phenol] as a Therapeutic Candidate for Asthma and Chronic Obstructive Pulmonary Disease. The Journal of Pharmacology and Experimental Therapeutics, March 2009, vol. 328, no. 3:758-765. (CH Tech NOIES)

           Marco Zaru, Chiara Sinico, Alessandro De Logu, Carla Caddeo, Francesco Lai, Maria Letizia Manca, Anna Maria Fadda. Rifampicin-loaded liposomes for the passive targeting to alveolar macrophages: in vitro and in vivo evaluation. Journal of Liposome Research, March 2009, Vol. 19, No. 1 , Pages 68-76. (CH Tech NOIES, Infectious agents)

           Manuel Osorio, Yanping Wu, Sunil Singh, Tod J. Merkel, Siba Bhattacharyya, Milan S. Blake and Dennis J. Kopecko. Anthrax Protective Antigen Delivered by Salmonella enterica Serovar Typhi Ty21a Protects Mice from a Lethal Anthrax Spore Challenge. Infect. Immun. April 2009 vol. 77 no. 4 1475-1482. (CH Tech NOIES, Infectious agents)

           John Doukas, Lisa Eide, Karin Stebbins, Adrienne Racanelli-Layton, Luis Dellamary, Michael Martin, Elena Dneprovskaia, Glenn Noronha, Richard Soll, Wolfgang Wrasidlo, Lisette M. Acevedo, David A. Cheresh. Aerosolized Phosphoinositide 3-Kinase γ/δ Inhibitor TG100-115 as a Therapeutic Candidate for Asthma and Chronic Obstructive Pulmonary Disease. Journal of Pharmacology and Experimental Therapeutics, 2009, Vol. 328, No. 3:758-765. (CH Tech NOIES)

           Bruce D. Naumann, Patricia A. Weideman, Ramesh Sarangapani, Shu-Cheih Hu, Rakesh Dixit and Edward V. Sargent. Investigations of the Use of Bioavailability Data to Adjust Occupational Exposure Limits for Active Pharmaceutical Ingredients. Toxicol. Sci. (2009) 112 (1): 196-210. (Rat Animal restraints)

           Karla D. Thrall, Angela D. Woodstock, Jolen J. Soelberg, Michael L. Gargas, John H. Kinzell, Richard A. Corley. A real-time methodology to evaluate the nasal absorption of volatile compounds in anesthetized animals. Inhalation Toxicology, May 2009, Vol. 21, No. 6 , Pages 531-536. (Rabbit plethysmograph)

           Teresa L. Leavens and Susan J. Borghoff. Physiologically Based Pharmacokinetic Model of Methyl Tertiary Butyl Ether and Tertiary Butyl Alcohol Dosimetry in Male Rats Based on Binding to a 2u-Globulin. Toxicological Sciences 109(2), 321–335 (2009). (Single animal whole-body tubes)

           Aris Polyzos, Thomas Ernst Schmid, Belem Piña-Guzmán, Betzabet Quintanilla-Vega, Francesco Marchetti. Differential sensitivity of male germ cells to mainstream and sidestream tobacco smoke in the mouse. Toxicology and Applied Pharmacology, Volume 237, Issue 3, 15 June 2009, Pages 298–305. (Cigarette smoke, CSM-SSM)

           Adam P. Matson, Roger S. Thrall, Ektor Rafti, and Lynn Puddington. Breastmilk from Allergic Mothers Can Protect Offspring from Allergic Airway Inflammation. Breastfeeding Medicine. September 2009, 4(3): 167-174. (BANG)

           Terry Gordon, Maarten Bosland. Strain-dependent differences in susceptibility to lung cancer in inbred mice exposed to mainstream cigarette smoke. Cancer Letters, Volume 275, Issue 2, 18 March 2009, Pages 213–220. (Cigarette smoke, 30 Port Automatic Smoking Machine)

           Errol M. Thomson, Andrew Williams, Carole L. Yauk, Renaud Vincent. Impact of nose-only exposure system on pulmonary gene expression. Inhalation Toxicology, July 2009, Vol. 21, No. s1 , Pages 74-82. (Animal restraints)

           Brian K. Heimbuch, Brenton R. Stone, Rashelle S. McDonald, Kimberly R. Kinney, April E. Lumley, Joseph D Wander. Assaying Benefits of Poly[styrene-4-(trimethylammonium)methyl Triiodide] in Respiratory Protection Devices. 2009 - DTIC Document, http://www.dtic.mil/dtic/tr/fulltext/u2/a515448.pdf. (CH Tech NOIES)

           Elizabeth M. Vancza, Sheung Pui Ng, Jack R. Harkema, Judith T. Zelikoff. The role of parity status on cigarette smoke-induced modulation of anti-tumor immune mechanisms. Journal of Immunotoxicology, June 2009, Vol. 6, No. 2 , Pages 94-103. (Cigarette smoke, 30 Port Automatic Smoking Machine)

           Lung Chi Chenab, Hua Fuan Lama, Edward J. Kima, John Gutya, and Mary O. Amdurab. Pulmonary effects of ultrafine coal fly ash inhaled by guinea pigs. Journal of Toxicology and Environmental Health, Volume 29, Issue 2, pages 169-184, 15 Oct 2009, 10.1080/15287399009531381. (WDF-II)

           Stephen J. Reynolds, Jason Nakatsu, Marvin Tillery, Thomas Keefe, John Mehaffy, Peter S. Thorne, Kelley Donham, Matthew Nonnenmann, Vijay Golla, and Patrick O'Shaughnessy. Field and wind tunnel comparison of four aerosol samplers using agricultural dusts. British Occupational Hygiene Society, 53 (6): 585-594, May 14, 2009, 10.1093/annhyg/mep021. (WDF-II)

           Jürgen Pauluhn. Retrospective analysis of 4-week inhalation studies in rats with focus on fate and pulmonary toxicity of two nanosized aluminum oxyhydroxides (boehmite) and pigment-grade iron oxide (magnetite): The key metric of dose is particle mass and not particle surface area. Toxicology, Elsevier, Vol 259.3, pages 140-148, 17 May 2009, doi:10.1016/j.tox.2009.02.012. (WDF-II)

           Jürgen Pauluhn. Subchronic 13-week Inhalation Exposure of Rats to Multiwalled Carbon Nanotubes: Toxic Effects are determined by Density of Agglomerate Structures, not fibrillar Structures. The Society of Toxicology, October 12, 2009, 10.1093/toxsci/kfp247. (WDF-II)

           Richard Fotland, John Bowers, William Jameson. Method and apparatus for producing uniform small portions of fine powders and articles thereof. U.S. Patent No. 7,632,533. 15 Dec. 2009. (WDF-II)

           Heidrun Ellinger-Ziegelbauer, Jürgen Pauluhn. Pulmonary toxicity of multi-walled carbon nanotubes (Baytubes®) relative to α-quartz following a single 6 h inhalation exposure of rats and a 3 months post-exposure period. Toxicology, Elsevier, vol 266.1, pages 16-29, 21 December 2009, doi:10.1016/j.tox.2009.10.007. (WDF-II)

           Jürgen Pauluhn. Pulmonary Toxicity and Fate of Agglomerated 10 nm and 40 nm Aluminum Oxyhydroxides (AlOOH) following 4-week Inhalation Exposure of Rats: Toxic Effects are determined by agglomerated, not primary Particle Size. The Society of Toxicology, February 27, 2009, 10.1093/toxsci/kfp046. (WDF-II)

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